Pastatyta XX a. pradžioje, veikė iki Antrojo pasaulinio karo. Pokario metais joje buvo druskos sandėlis ir gamybinės patalpos. Vėliau – mėginta įrengti elektrografijos cechą, tačiau miesto bendruomenė užprotestavo. Šiuo metu pastatas yra uždarytas. Prie sinagogos yra buvęs rabino namelis. Neveikianti.
Today, it is non-functioning. It is believed that the original wooden synagogue was built here in 1856, subsequently being replaced by the current stone at the end of the 19th century. In 1909 and 1911, Alytus was devastated by tremendous fires, however, the synagogue survived and was rebuilt. Some believe that in 1911 the synagogue was newly built according to an earlier plan. In the same year, the rabbi house was built next to it. The synagogue was made of yellowish and red bricks and was decorated with the main symbol of Judaism – a brickwork Star of David. During the Second World War, the synagogue was not bombarded and in the ensuing times of the Soviet regime the building was used as a warehouse.